Have you ever listened coastal inhabitants? Know what they think…

Coastal dynamics changes, caused by natural or man-made factors, can to give rise serious consequences, namely at urban areas, exposing coastal population at risk. In this context, the understanding of the way people perceive the coastal dynamics and their exposure to risk is essential for the land use management and Integrated Coastal Zone Management. To get the perception of coastal population, this research was based in a risk map proposed by Water Institute (1999) that classifies the Portuguese territory in three categories of risk: low, mean and high. A questionnaire was applied to the dwellings owners in coastal risk areas of Praia de Esmoriz, Praia de Cortegaça, Furadouro, Torreira, Praia da Barra, Costa Nova do Prado and Praia da Vagueira, during the summer season, in 2006. The questionnaire has as main objectives: coastal risks social perception; coastal dynamics social perception; identification of territorial and environmental changes in the coastal areas; identification of socio-environmental conflicts. A total of 418 questionnaires were completed which corresponds to 10% of the dwellings at risk in the study area. Almost all of respondents recognize the shoreline retreat and would accept having their houses relocated if it were confirmed that there home was in fact in danger, however the inquired population confirms to feeling safe near the sea. In other words, there is negligence of the coastal risks. It is necessary to inform the population of the problems that the coastal areas are suffering of and to get everyone involved in coastal issues

Learning from nature: Bio-Inspiration for damage-tolerant high-performance fibre-reinforced composites

Over millions of years Nature has attained highly optimized structural designs with remarkable toughness, strength, damage resistance and damage tolerance - properties that are so far difficult to combine in artificial high-performance fibre-reinforced polymers (HPFRPs). Recent studies, which have successfully replicated the structures and especially the toughening mechanisms found in flora and fauna, are reviewed in this work. At the core of the manufacturing of damage-tolerant bio-inspired composites, an understanding of the design principles and mechanisms is key. Universal and naturally-inherent design features, such as hierarchical- and organic-inorganic-structures as well as helical or fibrous arrangements of building blocks were found to promote numerous toughening mechanisms. Common to these features, the outstanding ability of diffusing damage at a sub-critical state has been identified as a powerful and effective mechanism to achieve high damage tolerance. Novel manufacturing processes suitable for HPFRP (such as tailored high-precision tape placement, micro-moulding, laser-engraving and additive manufacturing) have recently gained immense traction in the research community. This stems from the achievable and required geometrical complexity for HPFRPs and the replication of subtly balanced interaction between the material constituents. Even though trends in the literature clearly show that a bio-inspired material design philosophy is a successful strategy to design more efficient composite structures with enhanced damage tolerance and mechanical performance, Nature continues to offer new challenging opportunities yet to be explored, which could lead to a new era of HPFRP composites

Alcohol consumption among patients with hepatitis B infection in northern Portugal considering gender and hepatitis B virus genotype differences

Alcohol. 2010 Mar;44(2):149-56. Epub 2010 Jan 29. Alcohol consumption among patients with hepatitis B infection in northern Portugal considering gender and hepatitis B virus genotype differences. Mota A, Guedes F, Areias J, Pinho L, Cardoso MF. SourceInstituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Portugal. Abstract Alcohol abuse is an important public health problem. In Portugal with a population of 10 millions of inhabitants, there are around 10% of alcoholics or excessive alcohol drinkers and 1% of chronically infected patients with hepatitis B virus (HBV). To examine the characteristics of patients with higher levels of alcohol consumption and to investigate the association between alcohol consumption and liver damage a total of 298 chronically infected individuals, with HBV genotyped and submitted to liver biopsy, were classified with Child's grading and separated by habits of alcohol intake, less and greater than 20g/day. No significant differences were observed about genotype but genotypes A and D were predominant in both of them. A higher percentage of males (P<.001) were observed in the group with alcohol intake above 20g/day, as well a lower proportion of patients with HBeAg negativity (P< or =.035). In this group, biochemistry parameters, such as alanine aminotransferase (P=.006), aspartate aminotransferase (P=.001), gamma-glutamyl transferase (P<.001) were elevated in a significantly higher proportion than in the other group. The analysis of hematological parameters showed significantly lower values of platelets (P=.042) and mean corpuscular volume (P<.001) and significantly higher values of prothrombin time (P<.001) in the group with higher levels of alcohol consumption. The characteristics of biopsy (P<.001) and Child-Phug's classification (P=.002) revealed more severe results in this group. Logistic regression showed a positive association between liver damage and alcohol intake, increasing with age. In female patients, a strong positive association between alcohol intake and liver damage was also found (odds ratio: 9.379; 95% confidence interval: 0.859-468.422; P = .037); however, the most severe cases were only observed in women older than 45 years. In patients with HBV infection, alcohol is associated with a more severe liver disease. No evidence was found concerning association with HBV genotype. 2010 Elsevier Inc. All rights reserved

Epidemiological study of genotypes of hepatitis B virus in northerm Portugal

ed Virol. 2009 Jul;81(7):1170-6. Epidemiological study of genotypes of hepatitis B virus in northern Portugal. Mota A, Guedes F, Areias J, Pinho L, Cardoso MF. SourceInstituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal. Abstract While the overall prevalence of hepatitis B virus (HBV) infection in Portugal is around 1%, there are no published studies examining HBV genotypes in this country. This study aimed to survey HBV genotypes in the northern Portugal and to examine the possible associations between genotypes and gender, viral transmission routes, viral markers, viral load, and biochemical tests of liver function. The study sample consists of 340 patients with HBV infection of whom 42.9% were women. Tests were carried out for HBV genotypes and biochemical liver function while demographic information, including alcohol intake, was obtained from the patient files. The results indicate the predominance of genotype D (60.3%) and genotype A (31.5%). Intrafamilial transmission was predominant in female patients, while males were infected in equal proportions by perinatal, sexual, and intrafamilial transmission. Absence of HBeAg was found in a significantly smaller proportion of female patients with genotype D as compared to A (56.6% vs. 82.1%, P = 0.028). High viral load was associated significantly and independently with genotype D and HBeAg. Both alanine and aspartate aminotransferases (ALT and AST) were associated with gender and HBeAg. Thus, genotypes A and D were found to be the most prevalent in the north of Portugal. Patients infected with genotype D had higher levels of HBV DNA. HBeAg was associated with genotype D, viral load, and ALT and AST

Avaliação das necessidades energéticas no doente crítico

Introdução: Os doentes críticos são um grupo de do- entes francamente hipermetabólicos que necessitam de um suporte nutricional adequado às suas necessidades. Objectivos: Verificar o melhor método para determinar as neces- sidades energéticas de doentes críticos. Material e métodos: Estudo transversal analítico no qual foram recolhidos dados demográficos, determinado o consumo energético quer por calorimetria indirecta, quer pela fórmula de Harris-Benedict e além disso calculado o fator de stress de pacientes internados entre 2004 e 2009. Resultados: Incluíram- se neste estudo 139 doentes (33% feminino, 67% masculino). Foram efetuadas 298 medidas pela calorimetria indireta, com tempo útil médio de 9 horas, que foram compa- radas às necessidades energéticas calculadas a partir da equação de Harris-Benedict. Encontraram-se diferenças significativas entre os resultados obtidos. O consumo energético mensurado foi 27,9 Kcal/kg (mediana), e quando comparado à equação de Harris-Benedict, evidenciou-se um valor subestimado em 25% (7 Kcal/kg). A mediana do fator de stress encontrado para a correção da fórmula de Harris- Benedict foi de 1,31. Discussão e conclusão: Embora exista uma variabilidade do consumo energético nesses doentes, a fórmula de Harris-Benedict, quando associada a um fator stress entre 1,25 – 1,35, poderá ser um método eficaz na avaliação das necessidades nutricionais. Por outro lado, pode-se optar também por uma abordagem mais simplificada, utilizando valores energéticos entre 25 a 30 Kcal por quilograma de peso. Obviamente, a calorimetria indireta continua a ser o “gold standard’’ da avaliação do consumo energético, já que nos permite adequar as necessidades energéticas em função do consumo energético in- dividual de acordo com o gasto real de cada doente

ATRÉSIA ESOFÁGICA: 10 ANOS DE EXPERIÊNCIA DE UM SERVIÇO DE CUIDADOS INTENSIVOS PEDIÁTRICOS

Background/Purpose: Oesophageal atresia (OA) is a congenital malformation with a variable prognosis. The aims were to establish OA’s incidence in the central region, to characterize infants with OA admitted and to compare its clinical outcome after surgical repair, according to OA classification. Methods: A retrospective review of infants with OA admitted to a PICU, after surgical repair, between 2002 and 2011. Patient characteristics, OA’s classification, surgery, morbidity and mortality were analyzed. Two groups were compared according to OA classification. Results: Thirty-four infants were admitted, out of which 65% were male, with a median gestational age of 36 weeks and birth weight of 2310g. Nineteen of them presented other malformations, mainly cardiac. Nine cases were classified as long-gap OA. Fistula ligation and primary oesophageal anastomosis was the most common surgical option (n=27). Early complications occurred in 13 infants (38%), mostly anastomotic leak, and were similar according to gap length (p=0.704). PICU stay and mechanical ventilation were longer in long-gap OA patients (p=0.009 and p<0.001 respectively) and in infants with other malformations (p=0.027 and p=0.003 respectively). There was no mortality. Conclusions: The frequency of OA associated malformations implies a systematic screening of these patients. Gap length and presence of associated malformations were the major determinants of length of intensive care stay and ventilation days in OA patients

Assessment of different coastal defence structures to promote wave energy dissipation and sediments retention

Coastal areas are an apprized environment by society that will continue to expand rapidly. Traditional coastal protection structures are commonly deployed to protect coastal areas endangered by natural extreme weather events. However, due to their limited efficiency and very high costs, more efficient and sustainable strategies to deal with coastal erosion are imperative. This research work focuses on the assessment of engineering solutions to mitigate and delay coastal erosion. Three different structure geometries (triangular prism shape, single detached breakwater and group of two detached breakwaters) are analysed on a realistic bathymetry, using a combination of numerical models (SWAN and XBeach) to study the influence of those structures on the coastal hydro- and morphodynamics. SWAN was used for hydrodynamics and XBeach for hydrodynamics and morphodynamics assessments. In addition, a comparison between SWAN and XBeach hydrodynamics results was also performed. Structures considered in this study have regular shaped geometries, and are characterized in terms of their efficiency regarding wave height and wave energy dissipation considering different wave regimes and performance in terms of longterm beach morphodynamic impact (sediments accumulation and erosion). The analysis is concentrated in two scenarios, one for low and the other for highly energetic hydrodynamics (the most challenging to coastal zones defence). The obtained results allowed classifying their performance in terms of the impact on wave energy and wave height dissipation, and sediment erosion/deposition patterns.This work is supported by the Portuguese Foundation for Science and Technology (FCT) [PhD grant number SFRH/BD/141381/2018]. The authors also acknowledge the support provided by the project EcOffShorBe – Eco Offshore Built Environment, n. 37417, R&D cores in Copromoção, 14/SI/2017, NORTE-01-0247-FEDER-037417, supported by ANI (FEDER)